Generic Imitrex ( Sumatriptan )
Imitrex
Sumatriptan is a drug used for treating migraine attacks.
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Imitrex
25 mg
x
10 tablet
lei328.08
lei 273.39
lei 27.34 za tabletka
oszczędzać:  lei0.00
Imitrex
25 mg
x
20 tablet
lei568.71
lei 473.91
lei 23.70 za tabletka
oszczędzać:  lei72.92
Imitrex
25 mg
x
30 tablet
lei771.05
lei 642.53
lei 21.42 za tabletka
oszczędzać:  lei177.73
Imitrex
25 mg
x
60 tablet
lei1383.55
lei 1152.95
lei 19.23 za tabletka
oszczędzać:  lei486.72
Imitrex
25 mg
x
90 tablet
lei1864.80
lei 1553.99
lei 17.27 za tabletka
oszczędzać:  lei906.45
Imitrex
25 mg
x
120 tablet
lei2242.15
lei 1868.45
lei 15.59 za tabletka
oszczędzać:  lei1410.94
Imitrex
50 mg
x
10 tablet
lei551.43
lei 460.24
lei 46.03 za tabletka
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Imitrex
50 mg
x
20 tablet
lei885.89
lei 738.24
lei 36.91 za tabletka
oszczędzać:  lei182.29
Imitrex
50 mg
x
30 tablet
lei1198.57
lei 998.00
lei 33.27 za tabletka
oszczędzać:  lei382.81
Imitrex
50 mg
x
60 tablet
lei2155.60
lei 1795.53
lei 29.94 za tabletka
oszczędzać:  lei965.24
Imitrex
100 mg
x
10 tablet
lei583.33
lei 487.59
lei 48.76 za tabletka
oszczędzać:  lei0.00
Imitrex
100 mg
x
20 tablet
lei1048.18
lei 874.96
lei 43.75 za tabletka
oszczędzać:  lei100.26
Imitrex
100 mg
x
30 tablet
lei1417.32
lei 1180.30
lei 39.33 za tabletka
oszczędzać:  lei283.01
Imitrex
100 mg
x
60 tablet
lei2547.53
lei 2123.66
lei 35.41 za tabletka
oszczędzać:  lei801.17

Common use

Sumatriptan is a drug that is used for treating migraine attacks with or without the presence of an aura, to relieve cluster headache attacks. Sumatriptan is a Specific and selective agonist of 5-HT1-serotonin receptors localized mainly in blood vessels of the brain. Migraine headaches are believed to be stipulated by widening of blood vessels in the brain. Sumatriptan causes vasoconstriction of the carotid arterial bed which provides extracranial and intracranial tissues with blood without a significant impact on cerebral blood flow. It also inhibits activity of receptor which are responsible for transmission of pain signals by nerves to the brain.



Dosage and direction

Treatment with Sumatripan should be done just before the starting of a migraine attack. Recommended oral dose of adults is 25-50 mg, the dose maybe increased up to 100 mg if necessary. The medication is effective at any stage of the attack but if it does not help during the attack additional dose should not be taken. Treatment with Sumatriptan should be continued to prevent the next attack. Tablet of Sumatriptan should be swallowed whole, take it with a big glass of water. Usual intranasal dose of 5-20 mg may be increased to the maximum dose of 40 mg daily.



Precautions

Sumatriptan is used only to treat an acute, classic migraine attack or a cluster headache, it should not be used for treatment of certain unusual types of migraine. Patients with uncontrolled high blood pressure should not use Sumatriptan.



Contraindications

Hypersensitivity, basal, ophtalmoplegic, hemiplegic forms of migraine, ischemic heart disease (including suspected it), angina (including angina Printsmetala), myocardial infarction (also in history), hypertension, peripheral arterial occlusive disease, stroke or transient cerebrovascular accident (also in history), liver and kidney failure. Cautiousness should be exercised in patients with epilepsy (including any condition with low epileptic threshold), hypertension, pregnancy, breastfeeding, in infants and adolescents (younger than 18 y.o.), in patients older than 65 y.o.; simultaneous intake of medications which contain ergotamine and its derivatives, MAO inhibitors, and also during the period of 14 days after their cancellation.



Possible side effect

This medication is usually well tolerated and adverse reactions are not expected. Most frequent side effects include pain or tightness in the chest or throat, tingling, flushing, weakness, dizziness, abdominal discomfort, sweating, nasal irritation, and injection site reactions. Allergic reactions as adverse reactions of organism to Sumatriptan are also possible.



Drug interaction

Co-administration with ergotamine and medications containing ergotamin may develop a continued spasm of blood vessels (the interval between administration of these medications must be at least 24 h). Interaction of Sumatriptan and MAO inhibitors (isocarboxazid (Marplan), phenelzine (Nardil), tranylcypromine (Parnate), and procarbazine (Matulane)) is also possible resulting in increased concentration of Sumatriptan. Concomitant use of Sumatriptan with selective serotonin reuptake inhibitors or SSRIs, including fluoxetine (Prozac), citalopram (Celexa), paroxetine (Paxil), and sertraline (Zoloft) or serotonin and norepinephrine reuptake inhibitors, including venlafaxine (Effexor), duloxetine (Cymbalta), and desvenlafaxine (Pristiq) may promote weakness, hyperreflexia and poor coordination of movements.



Missed dose

Sumatriptan is not meant for regular use, it is taken only during an attack.



Overdose

Be especially attentive to such symptoms as bluish tinge to the skin, convulsions, dilated pupils, inactivity, lack of coordination, paralysis, redness in the arms and legs, skin changes at the site of injection, slow breathing, sluggishness, tremor as they may be signs of Sumatriptan overdose. Inform your health care advisor immediately about your condition nor seek for emergency medical help.



Storage

Store this medication at a temperature of 2-30 C (36-86 F) in a tight container resistant to light and moisture.



Disclaimer

We provide only general information about medications which does not cover all directions, possible drug integrations, or precautions. Information at the site cannot be used for self-treatment and self-diagnosis. Any specific instructions for a particular patient should be agreed with your health care adviser or doctor in charge of the case. We disclaim reliability of this information and mistakes it could contain. We are not responsible for any direct, indirect, special or other indirect damage as a result of any use of the information on this site and also for consequences of self-treatment.


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